The origin of the eukaryotic cell was a milestone in the evolution of life. Although eukaryotes use the same genetic code and metabolic processes as prokaryotes, their higher level of organizational complexity has permitted the development of truly multicellular organisms. Without eukaryotes, the world would lack mammals, birds, fish, invertebrates, fungi, plants, and complex single-celled organisms.
Sunday, January 23, 2011
Eukaryotic Cells
The origin of the eukaryotic cell was a milestone in the evolution of life. Although eukaryotes use the same genetic code and metabolic processes as prokaryotes, their higher level of organizational complexity has permitted the development of truly multicellular organisms. Without eukaryotes, the world would lack mammals, birds, fish, invertebrates, fungi, plants, and complex single-celled organisms.
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Prokaryotic Cells
Cells that lack a membrane-bound nucleus are called prokaryotes (from the Greek meaning before nuclei). These cells have few internal structures that are distinguishable under a microscope. Cells in the monera kingdom such as bacteria and cyanobacteria (also known as blue-green algae) are prokaryotes.
Prokaryotic cells differ significantly from eukaryotic cells. They don't have a membrane-bound nucleus and instead of having chromosomal DNA, their genetic information is in a circular loop called a plasmid. Bacterial cells are very small, roughly the size of an animal mitochondrion (about 1-2µm in diameter and 10 µm long). Prokaryotic cells feature three major shapes: rod shaped, spherical, and spiral. Instead of going through elaborate replication processes like eukaryotes, bacterial cells divide by binary fission. Bacteria perform many important functions on earth. They serve as decomposers, agents of fermentation, and play an important role in our own digestive system. Also, bacteria are involved in many nutrient cycles such as the nitrogen cycle, which restores nitrate into the soil for plants. Unlike eukaryotic cells that depend on oxygen for their metabolism, prokaryotic cells enjoy a diverse array of metabolic functions. For example, some bacteria use sulfur instead of oxygen in their metabolism.
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DNA translation
In the synthesis or production of proteins, a process of decoding the 'messenger Ribonucleic Acid' or mRNA takes place. It is the first step, and is known as translation. The mRNAs decoded in translation are obtained from a process known as transcription. The translation process takes place in the cell cytoplasm, specifically where the cell organelle, ribosome is present. Translation produces polypeptides as a result of decoding of the mRNA.
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Transcription
DNA transcription is a process that involves the transcribing of genetic information from DNA to RNA. The transcribed DNA message is used to produce proteins. DNA is housed within the nucleus of our cells. It controls cellular activity by coding for the production of enzymes and proteins. The information in DNA is not directly converted into proteins, but must first be copied into RNA. This ensures that the information contained within the DNA does not become tainted.
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DNA replication
The new strands are assembled from deoxynucleoside triphosphates. Each incoming nucleotide is covalently linked to the "free" 3' carbon atom on the pentose (figure) as the second and third phosphates are removed together as a molecule of pyrophosphate (PPi). The nucleotides are assembled in the order that complements the order of bases on the strand serving as the template. Thus each C on the template guides the insertion of a G on the new strand, each G a C, and so on. When the process is complete, two DNA molecules have been formed identical to each other and to the parent molecule.
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