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Gene Therapy for Metastatic Melanoma in Mice Produces Complete Remission

Cancer researchers report a potent anti-tumor gene introduced into mice with metastatic melanoma has resulted in permanent immune reconfiguration and produced a complete remission of their cancer, according to an article to be published in the December 2010 issue of the Journal of Clinical Investigation. ... > full story

Sunday, January 23, 2011

Eukaryotic Cells


 


 
A cell that contains membrane-bound compartments in which specific metabolic activities take place. Most important among these compartments is the nucleus, which houses the eukaryotic cell's . It is DNA this nucleus that gives the eukaryote – literally, "true nucleus" – its name. Eukaryotic organisms also have other specialized, membrane-bounded structures, called organelles, which are small structures within cells that perform dedicated functions. Eukaryotic cells are typically 10 to 100 micrometers across, or about 10 times the size of prokaryotic cells. The set of ideas most favored by biologists to explain how eukaryotic cells first came about is called the endosymbiotic theory. This theory is able to account well for the fact that two of the organelles found in eukaryotic cells, mitochondrias and chloroplasts, have their own DNA that is completely distinct from the DNA housed in the nucleus. According to the endosymbiotic theory, the eukaryotic cell evolved from a symbiotic community of prokaryotic cells. Specifically, the mitochondria and the chloroplasts are what remains of ancient symbiotic oxygen-breathing bacteria and cyanobacteria, respectively, whereas the rest of the cell seems to be derived from an ancestral archaean prokaryote cell.
The origin of the eukaryotic cell was a milestone in the evolution of life. Although eukaryotes use the same genetic code
 and metabolic processes as prokaryotes, their higher level of organizational complexity has permitted the development of truly multicellular organisms. Without eukaryotes, the world would lack mammals, birds, fish, invertebrates, fungi, plants, and complex single-celled organisms. 



 

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